The proposed research plan has three goals: (1) increasing our understanding of the relationship between environmental factors and the health and academic performance of students, teachers and staff; (2) evaluating the use and effectiveness of indoor environmental quality (IEQ) measures used in high performance school buildings; and (3) promoting an understanding of the importance of IEQ in schools and IEQ targets for high performance buildings and informing the next generation of standards for the sustainable design of schools.